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Best Open Source python Libraries

A curated list of the most popular GitHub repositories tagged with python. Select any project to visualize its architecture and dive into the codebase using GitPulse's AI engine.

#1Significant-Gravitas/AutoGPT

AutoGPT is the vision of accessible AI for everyone, to use and to build on. Our mission is to provide the tools, so that you can focus on what matters.

184,162Python
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#2huggingface/transformers

🤗 Transformers: the model-definition framework for state-of-the-art machine learning models in text, vision, audio, and multimodal models, for both inference and training.

160,460Python
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#3odoo/odoo

Odoo. Open Source Apps To Grow Your Business.

50,583Python
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#4ComposioHQ/composio

Composio powers 1000+ toolkits, tool search, context management, authentication, and a sandboxed workbench to help you build AI agents that turn intent into action.

28,149TypeScript
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#5openai/openai-agents-python

A lightweight, powerful framework for multi-agent workflows

26,164Python
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#6nautechsystems/nautilus_trader

Production-grade Rust-native trading engine with deterministic event-driven architecture

22,630Rust
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#7Skyvern-AI/skyvern

Automate browser based workflows with AI

21,562Python
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#8python/mypy

Optional static typing for Python

20,412Python
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#9microsoft/aspire

Aspire is the tool for code-first, extensible, observable dev and deploy.

5,912C#
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#10domoticz/domoticz

Free open source home automation system for Linux, Windows, Raspberry Pi. Supports Z-Wave, Zigbee, MQTT, and 150+ devices.

3,753C++
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#11apache/datafusion-ballista

Apache DataFusion Ballista Distributed Query Engine

2,030Rust
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#12bruin-data/bruin

Build data pipelines with SQL and Python, ingest data from different sources, add quality checks, and build end-to-end flows.

1,585Go
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#13Soju06/codex-lb

Codex/ChatGPT multiple account load balancer & proxy with usage tracking, dashboard, and OpenCode-compatible endpoints

1,236Python
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#14devpi/devpi

Python PyPi staging server and packaging, testing, release tool

1,170Python
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#15beenuar/AiSOC

Open-source AI-powered Security Operations Center — alert fusion, purple-team drills, agent-assisted triage, MITRE ATT&CK investigation. MIT-licensed, self-hostable.

420Python
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#16Epodonios/bulk-xray-v2ray-vless-vmess-...-configs

free vmess vless trojan shadowsocks live v2ray_xray configs splitted by country

349Python
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#17Linuxfabrik/monitoring-plugins

230+ monitoring plugins for Icinga, Nagios & friends. Python 3.9+, all platforms. Smart defaults, auto-discovery, consistent cross-platform metrics, minimal dependencies.

274Python
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#18patx/micropie

MicroPie is an ultra-micro ASGI Python web framework that gets out of your way.

230Python
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